Projects

ProjectTitlePrincipal Investigators
Project Area A: Scientific Projects

A01

Structural and functional organization of endocytic scaffolds within the periactive zone

Haucke (FMP; FUB)

Maritzen (FMP)

A03

In vivo analysis of active zone assembly

Sigrist (FUB)

Petzoldt (FUB)

A04

Spatiotemporal model of neuronal signaling and its regulation by presynaptic membrane scaffolds

Noé (FUB)

A05

The Role of the Rim-binding protein AZ scaffold in regulating neurotransmitter release at diverse central synapses

Rosenmund (NWFZ, CHA)

Schmitz (CHA)

A06

Organization of the synaptic active zone scaffold by Bruchpilot and RIM-binding protein 

Wahl (FUB)

Sigrist (FUB)

A07

Regulation of SH3 domain-based scaffolds in clathrin-mediated endocytosis

Freund (FUB)

Haucke (FMP; FUB)

A09

Scaffolding of mechanotransduction domains in migratinfg and non-migrating cells

Lewin (MDC)

Hammes-Lewin (MDC)

A11

Functional analysis of septin scaffolds assembled at the plasma membrane during cytokinesis

Krauß(FMP)

Ewers (FUB)

A12

Structural and functional examinations of nucleotide-dependent membrane scaffolds

Daumke (MDC)

A13

Golgi-associated protein scaffolds regulating receptor targeting and hormone secretion

Schürmann (DIfE)

A16

A PRG2-PTEN based membrane scaffold involved in the formation of axon branches

Eickholt (CHA)

A17

Protein scaffolds in synaptic endomembrane degradation

Hiesinger (FUB)

A18

Synaptic scaffold proteins regulate presynaptic proteostasis

Garner (DZNE)

A19

Functional regulation of post-synaptic scaffold proteins

Shoichet (CHA)

A21

A global role of alternative splicing in the secretory pathway: The COPII scaffold and beyond

Heyd (FUB)

A22

Investigating the role of the membrane-associated Cerebral Cavernous Malformations (CCM) protein scaffold in biomechanical signaling

Seyfried (UP)

A23

Characterization of the membrane scaffold complexes that tune photoreceptor neuron function

Wernet (FUB)

A25

Nanoscale organization of adaptor scaffolds involved in polarized cargo sorting at the trans-Golgi network (TGN)

Bottanelli (FUB)

A26

Modeling mechanisms of membrane shaping, fusionn, and fission in endo- and exocytosis by protein scaffolds

Kozlov (TAU)

A27

Synaptic scaffolds regulating cholinergic Drosophila synapses

Owald (CHA)
Project Area Z: Central Projects, Graduate Training and Administration

Z02

Advanced and super-resolution imaging to resolve the nanoscale structure and dynamics of membrane scaffolds

Schmoranzer(CHA)

Ewers (FUB)

Z03

Proteomics  platform for protein interaction mapping

Freund (FUB)

Liu (FMP)

Z05

Three-dimensional cryo-electron microscopy

Spahn (CHA)
Graduate Training  

MGK

Integrated Research Training Group

Ewers (FUB)

Administration  

Z01

Central Tasks - SFB Office and Administration

Sigrist (FUB)

CHA: Charité - Universitätsmedizin Berlin

DIfE: German Institute for Nutrition Research

DZNE: Deutsches Zentrum für Neurodegenerative Erkrankungen

FMP: Leibniz-Institut für Molekulare Pharmakologie

FUB: Freie Universität Berlin

MDC: Max-Delbrück-Center for Molecular Medicine

NWFZ: Neuroscience Research Center at the Charité

UP: Universität Potsdam