Springe direkt zu Inhalt

Selected Publications of the Principal Investigators

  • Turrel O, Ramesh N, Escher MJF, Pooryasin A, Sigrist SJ
    Transient active zone remodeling in the Drosophila mushroom body supports memory
    Curr Biol. 32(22) doi: 10.1016/j.cub.2022.10.017
  • Zehtabian A, Müller PM, Goisser M, Obendorf L, Jänisch L, Hümpfer N, Rentsch J, Ewers H
    Precise measurement of nanoscopic septin ring structures with deep learning-assisted quantitative superresolution microscopy
    Mol Biol Cell. 33(8) doi: 10.1091/mbc.E22-02-0039
  • Ojeda-Alonso J, Bégay V, Garcia-Contreras JA, Campos-Pérez AF, Purfürst B, Lewin GR
    Lack of evidence for participation of TMEM150C in sensory mechanotransduction
    J Gen Physiol. 154(12) doi: 10.1085/jgp.202213098
  • Bouazza-Arostegui B, Camacho M, Brockmann MM, Zobel S, Rosenmund C
    Deconstructing Synaptotagmin-1's Distinct Roles in Synaptic Vesicle Priming and Neurotransmitter Release
    J Neurosci. 42(14) doi: 10.1523/JNEUROSCI.1945-21.2022
  • Schmerl B, Gimber N, Kuropka B, Stumpf A, Rentsch J, Kunde SA, von Sivers J, Ewers H, Schmitz D, Freund C, Schmoranzer J, Rademacher N, Shoichet SA
    The synaptic scaffold protein MPP2 interacts with GABAA receptors at the periphery of the postsynaptic density of glutamatergic synapses
    PLoS Biol. 20(3) doi: 10.1371/journal.pbio.3001503
  • Haimov E, Urbakh M, Kozlov MM
    Negative tension controls stability and structure of intermediate filament networks
    Sci Rep. 12(1) doi: 10.1038/s41598-021-02536-0
  • Gimber N, Strauss S, Jungmann R, Schmoranzer R
    Simultaneous multicolor DNA-PAINT without sequential fluid exchange using spectral demixing
    Nano Letters (In Press. bioRxiv version available)
  • Voss M, Kleinau G, Gimber N, Janek K, Bredow C, Thery F, Impens F, Schmoranzer J, Scheerer P, Kloetzel PM, Beling A
    A cytosolic disulfide bridge-supported dimerization is crucial for stability and cellular distribution of Coxsackievirus B3 protein 3A
    FEBS J. doi: 10.1111/febs.16368
  • Tukker JJ, Beed P, Brecht M, Kempter R, Moser EI, Schmitz D.
    Microcircuits for spatial coding in the medial entorhinal cortex
    Physiol Rev. 102(2) doi: 10.1152/physrev.00042.2020

  • Jiang PL, Wang C, Diehl A, Viner R, Etienne C, Nandhikonda P, Foster L, Bomgarden RD, Liu F
    A Membrane-Permeable and Immobilized Metal Affinity Chromatography (IMAC) Enrichable Cross-Linking Reagent to Advance In Vivo Cross-Linking Mass Spectrometry
    Angew Chem Int Ed Engl. e202113937 doi: 10.1002/anie.202113937
  • Lima DB, Zhu Y, Liu F
    XlinkCyNET: A Cytoscape Application for Visualization of Protein Interaction Networks Based on Cross-Linking Mass Spectrometry Identifications
    J Proteome Res. 20(4) doi: 10.1021/acs.jproteome.0c00957
  • Wang N, Clark LD, Gao Y, Kozlov MM, Shemesh T, Rapoport TA
    Mechanism of membrane-curvature generation by ER-tubule shaping proteins
    Nat Commun. 12(1) doi: 10.1038/s41467-020-20625-y
  • Golani G, Leikina E, Melikov K, Whitlock JM, Gamage DG, Luoma-Overstreet G, Millay DP, Kozlov MM, Chernomordik LV
    Myomerger promotes fusion pore by elastic coupling between proximal membrane leaflets and hemifusion diaphragm
    Nat Commun. 12(1) doi: 10.1038/s41467-020-20804-x
  • Ben Zucker, Gonen Golani, Michael M. Kozlov
    Model for ring closure in ER tubular network dynamics
    bioRxiv 2021.11.18.469198; doi: https://doi.org/10.1101/2021.11.18.469198
  • Kraushar ML, Krupp F, Harnett D, Turko P, Ambrozkiewicz MC, Sprink T, Imami K, Günnigmann M, Zinnall U, Vieira-Vieira CH, Schaub T, Münster-Wandowski A, Bürger J, Borisova E, Yamamoto H, Rasin MR, Ohler U, Beule D, Mielke T, Tarabykin V, Landthaler M, Kramer G, Vida I, Selbach M, Spahn CMT
    Protein Synthesis in the Developing Neocortex at Near-Atomic Resolution Reveals Ebp1-Mediated Neuronal Proteostasis at the 60S Tunnel Exit
    Mol Cell. 81(2) doi: 10.1016/j.molcel.2020.11.037
  • Okada AK, Teranishi K, Ambroso MR, Isas JM, Vazquez-Sarandeses E, Lee JY, Melo AA, Pandey P, Merken D, Berndt L, Lammers M, Daumke O, Chang K, Haworth IS, Langen R
    Lysine acetylation regulates the interaction between proteins and membranes
    Nat Commun. 12(1) doi: 10.1038/s41467-021-26657-2
  • Wilhelmi I, Grunwald S, Gimber N, Popp O, Dittmar G, Arumughan A, Wanker EE, Laeger T, Schmoranzer J, Daumke O, Schürmann A
    The ARFRP1-dependent Golgi scaffolding protein GOPC is required for insulin secretion from pancreatic β-cells
    Mol Metab. 45 doi: 10.1016/j.molmet.2020.101151
  • Geertsema HJ, Aimola G, Fabricius V, Fuerste JP, Kaufer BB, Ewers H
    Left-handed DNA-PAINT for improved super-resolution imaging in the nucleus
    Nat Biotechnol. 39(5) doi: 10.1038/s41587-020-00753-y
  • Gao M, Thielhorn R, Rentsch J, Honigmann A, Ewers H
    Expansion STED microscopy (ExSTED)
    Methods Cell Biol. 161 doi: 10.1016/bs.mcb.2020.06.001
  • Kowalczyk I, Lee C, Schuster E, Hoeren J, Trivigno V, Riedel L, Görne J, Wallingford JB, Hammes A, Feistel K
    Neural tube closure requires the endocytic receptor Lrp2 and its functional interaction with intracellular scaffolds
    Development 148(2) doi: 10.1242/dev.195008
  • Mecklenburg N, Kowalczyk I, Witte F, Görne J, Laier A, Mamo TM, Gonschior H, Lehmann M, Richter M, Sporbert A, Purfürst B, Hübner N, Hammes A
    Identification of disease-relevant modulators of the SHH pathway in the developing brain
    Development. 148(17) doi: 10.1242/dev.199307
  • Oldani S, Moreno-Velasquez L, Faiss L, Stumpf A, Rosenmund C, Schmitz D, Rost BR
    SynaptoPAC, an optogenetic tool for induction of presynaptic plasticityJ Neurochem. 156(3) doi: 10.1111/jnc.15210
  • Sammons RP, Tzilivaki A, Schmitz D
    Local Microcircuitry of PaS Shows Distinct and Common Features of Excitatory and Inhibitory Connectivity
    Cereb Cortex. 32(1) doi: 10.1093/cercor/bhab195
  • Orlando M, Dvorzhak A, Bruentgens F, Maglione M, Rost BR, Sigrist SJ, Breustedt J, Schmitz D
    Recruitment of release sites underlies chemical presynaptic potentiation at hippocampal mossy fiber boutons
    PLoS Biol. 19(6) doi: 10.1371/journal.pbio.3001149
  • Trnka F, Hoffmann C, Wang H, Sansevrino R, Rankovic B, Rost BR, Schmitz D, Schmidt HB, Milovanovic D
    Aberrant Phase Separation of FUS Leads to Lysosome Sequestering and Acidification
    Front Cell Dev Biol. 9 doi: 10.3389/fcell.2021.716919
  • Rodríguez de Los Santos M, Rivalan M, David FS, Stumpf A, Pitsch J, Tsortouktzidis D, Velasquez LM, Voigt A, Schilling K, Mattei D, Long M, Vogt G, Knaus A, Fischer-Zirnsak B, Wittler L, Timmermann B, Robinson PN, Horn D, Mundlos S, Kornak U, Becker AJ, Schmitz D, Winter Y, Krawitz PM
    A CRISPR-Cas9-engineered mouse model for GPI-anchor deficiency mirrors human phenotypes and exhibits hippocampal synaptic dysfunctionsProc Natl Acad Sci U S A. 118(2) doi: 10.1073/pnas.2014481118
  • Imbrosci B, Nitzan N, McKenzie S, Donoso JR, Swaminathan A, Böhm C, Maier N, Schmitz D
    Subiculum as a generator of sharp wave-ripples in the rodent hippocampus
    Cell Rep 35(3) doi: 10.1016/j.celrep.2021.109021
  • Paolini A, Fontana F, Pham VC, Rödel CJ, Abdelilah-Seyfried S
    Mechanosensitive Notch-Dll4 and Klf2-Wnt9 signaling pathways intersect in guiding valvulogenesis in zebrafish
    Cell Rep 37(1); doi: 10.1016/j.celrep.2021.109782
  • Ramesh N, Escher MJF, Mampell MM, Böhme MA, Götz TWB, Goel P, Matkovic T, Petzoldt AG, Dickman D, Sigrist SJ
    Antagonistic interactions between two Neuroligins coordinate pre- and postsynaptic assembly
    Curr Biol. 31(8); doi: 10.1016/j.cub.2021.01.093
  • Liang Y, Piao C, Beuschel CB, Toppe D, Kollipara L, Bogdanow B, Maglione M, Lützkendorf J, See JCK, Huang S, Conrad TOF, Kintscher U, Madeo F, Liu F, Sickmann A, Sigrist SJ
    eIF5A hypusination, boosted by dietary spermidine, protects from premature brain aging and mitochondrial dysfunction
    Cell Rep 35(2); doi: 10.1016/j.celrep.2021.108941
  • Götz TWB, Puchkov D, Lysiuk V, Lützkendorf J, Nikonenko AG, Quentin C, Lehmann M, Sigrist SJ, Petzoldt AG
    Rab2 regulates presynaptic precursor vesicle biogenesis at the trans-Golgi
    J Cell Biol. 220(5); doi: 10.1083/jcb.202006040

  • Schnirch L, Nadler-Holly M, Siao SW, Frese CK, Viner R, Liu F
    Expanding the Depth and Sensitivity of Cross-Link Identification by Differential Ion Mobility Using High-Field Asymmetric Waveform Ion Mobility Spectrometry
    Anal Chem. 92(15) doi: 10.1021/acs.analchem.0c01273
  • Haimov E, Windoffer R, Leube RE, Urbakh M, Kozlov MM
    Model for Bundling of Keratin Intermediate Filaments
    Biophys J. 119(1) doi: 10.1016/j.bpj.2020.05.024
  • Parton RG, Kozlov MM, Ariotti N
    Caveolae and lipid sorting: Shaping the cellular response to stress
    J Cell Biol. 219(4) doi: 10.1083/jcb.201905071
  • Zieger HL, Kunde SA, Rademacher N, Schmerl B, Shoichet SA
    Disease-associated synaptic scaffold protein CNK2 modulates PSD size and influences localisation of the regulatory kinase TNIK
    Sci Rep 10(1) doi: 10.1038/s41598-020-62207-4
  • Mathejczyk TF, Wernet MF
    Modular assays for the quantitative study of visually guided navigation in both flying and walking flies
    J Neurosci Methods 340 doi: 10.1016/j.jneumeth.2020.108747
  • Lee CY, Petkova M, Morales-Gonzalez S, Gimber N, Schmoranzer J, Meisel A, Böhmerle W, Stenzel W, Schuelke M, Schwarz JM
    A spontaneous missense mutation in the chromodomain helicase DNA-binding protein 8 (CHD8) gene: a novel association with congenital myasthenic syndrome
    Neuropathol Appl Neurobiol. 46(6) doi: 10.1111/nan.12617
  • Eede P, Obst J, Benke E, Yvon-Durocher G, Richard BC, Gimber N, Schmoranzer J, Böddrich A, Wanker EE, Prokop S, Heppner FL
    Interleukin-12/23 deficiency differentially affects pathology in male and female Alzheimer's disease-like mice
    EMBO Rep 21(3) doi: 10.15252/embr.201948530
  • Kessissoglou IA, Langui D, Hasan A, Maral M, Dutta SB, Hiesinger PR, Hassan BA
    The Drosophila amyloid precursor protein homologue mediates neuronal survival and neuroglial interactions
    PLoS Biol. 18(12) doi: 10.1371/journal.pbio.3000703
  • Kiral FR, Linneweber GA, Mathejczyk T, Georgiev SV, Wernet MF, Hassan BA, von Kleist M, Hiesinger PR
    Autophagy-dependent filopodial kinetics restrict synaptic partner choice during Drosophila brain wiring
    Nat Commun. 11(1) doi: 10.1038/s41467-020-14781-4
  • Agi E, Kulkarni A, Hiesinger PR
    Neuronal strategies for meeting the right partner during brain wiring
    Curr Opin Neurobiol. 63 doi: 10.1016/j.conb.2020.01.002
  • Linneweber GA, Andriatsilavo M, Dutta SB, Bengochea M, Hellbruegge L, Liu G, Ejsmont RK, Straw AD, Wernet M, Hiesinger PR, Hassan BA
    A neurodevelopmental origin of behavioral individuality in the Drosophila visual system
    Science. 367(6482) doi: 10.1126/science.aaw7182
  • Grunwald S, Hopf LVM, Bock-Bierbaum T, Lally CCM, Spahn CMT, Daumke O
    Divergent architecture of the heterotrimeric NatC complex explains N-terminal acetylation of cognate substrates
    Nat Commun. 11(1) doi: 10.1038/s41467-020-19321-8
  • Matthaeus C, Lahmann I, Kunz S, Jonas W, Melo AA, Lehmann M, Larsson E, Lundmark R, Kern M, Blüher M, Olschowski H, Kompa J, Brügger B, Müller DN, Haucke V, Schürmann A, Birchmeier C, Daumke O
    EHD2-mediated restriction of caveolar dynamics regulates cellular fatty acid uptake
    Proc Natl Acad Sci U S A. 117(13) doi: 10.1073/pnas.1918415117
  • Xavier A, Al-Zeer MA, Meyer TF, Daumke O
    hGBP1 Coordinates Chlamydia Restriction and Inflammasome Activation through Sequential GTP Hydrolysis
    Cell Rep 31(7) doi: 10.1016/j.celrep.2020.107667
  • Li JH, Santos-Otte P, Au B, Rentsch J, Block S, Ewers H
    Directed manipulation of membrane proteins by fluorescent magnetic nanoparticles
    Nat Commun. 11(1) doi: 10.1038/s41467-020-18087-3
  • Falck J, Bruns C, Hoffmann-Conaway S, Straub I, Plautz EJ, Orlando M, Munawar H, Rivalan M, Winter Y, Izsvák Z, Schmitz D, Hamra FK, Hallermann S, Garner CC, Ackermann F
    Loss of Piccolo Function in Rats Induces Cerebellar Network Dysfunction and Pontocerebellar Hypoplasia Type 3-like Phenotypes
    J Neurosci. 40(14) doi: 10.1523/JNEUROSCI.2316-19.2020
  • Beed P, de Filippo R, Holman C, Johenning FW, Leibold C, Caputi A, Monyer H, Schmitz D
    Layer 3 Pyramidal Cells in the Medial Entorhinal Cortex Orchestrate Up-Down States and Entrain the Deep Layers Differentially
    Cell Rep 33(10) doi: 10.1016/j.celrep.2020.108470
  • Traub RD, Whittington MA, Maier N, Schmitz D, Nagy JI
    Could electrical coupling contribute to the formation of cell assemblies?
    Rev Neurosci. 31(2) doi: 10.1515/revneuro-2019-0059
  • Zarebidaki F, Camacho M, Brockmann MM, Trimbuch T, Herman MA, Rosenmund C
    Disentangling the Roles of RIM and Munc13 in Synaptic Vesicle Localization and Neurotransmission
    J Neurosci 40(49); doi: 10.1523/JNEUROSCI.1922-20.2020
  • Pechstein A, Tomilin N, Fredrich K, Vorontsova O, Sopova E, Evergren E, Haucke V, Brodin L, Shupliakov O
    Vesicle Clustering in a Living Synapse Depends on a Synapsin Region that Mediates Phase Separation
    Cell Rep 30(8); doi: 10.1016/j.celrep.2020.01.092
  • Fontana F, Haack T, Reichenbach M, Knaus P, Puceat M, Abdelilah-Seyfried S
    Antagonistic Activities of Vegfr3/Flt4 and Notch1b Fine-tune Mechanosensitive Signaling during Zebrafish Cardiac Valvulogenesis
    Cell Rep 32(2); doi: 10.1016/j.celrep.2020.107883
  • Sadeghi M, Noé F
    Large-scale simulation of biomembranes incorporating realistic kinetics into coarse-grained models
    Nat Commun. 11(1); doi: 10.1038/s41467-020-16424-0 
  • Zieger HL, Kunde SA, Rademacher N, Schmerl B, Shoichet SA
    Disease-associated synaptic scaffold protein CNK2 modulates PSD size and influences localisation of the regulatory kinase TNIK
    Sci Rep 10(1); doi: 10.1038/s41598-020-62207-4
  • Maglione M, Kochlamazashvili G, Eisenberg T, Rácz B, Michael E, Toppe D, Stumpf A, Wirth A, Zeug A, Müller FE, Moreno-Velasquez L, Sammons RP, Hofer SJ, Madeo F, Maritzen T, Maier N, Ponimaskin E, Schmitz D, Haucke V, Sigrist SJ
    Spermidine protects from age-related synaptic alterations at hippocampal mossy fiber-CA3 synapses
    Sci Rep 9(1); doi: 10.1038/s41598-019-56133-3
  • Petzoldt AG, Götz TWB, Driller JH, Lützkendorf J, Reddy-Alla S, Matkovic-Rachid T, Liu S, Knoche E, Mertel S, Ugorets V, Lehmann M, Ramesh N, Beuschel CB, Kuropka B, Freund C, Stelzl U, Loll B, Liu F, Wahl MC, Sigrist SJ
    RIM-binding protein couples synaptic vesicle recruitment to release sites
    J Cell Biol 219(7); doi: 10.1083/jcb.201902059

  • Lehmann M, Lukonin I, Noé F, Schmoranzer J, Clementi C, Loerke D, Haucke V
    Nanoscale coupling of endocytic pit growth and stability
    Sci Adv. 25(11) doi: 10.1126/sciadv.aax5775
  • Giesecke T, Himmerkus N, Leipziger J, Bleich M, Koshimizu TA, Fähling M, Smorodchenko A, Shpak J, Knappe C, Isermann J, Ayasse N, Kawahara K, Schmoranzer J, Gimber N, Paliege A, Bachmann S, Mutig K
    Vasopressin Increases Urinary Acidification via V1a Receptors in Collecting Duct Intercalated Cells
    J Am Soc Nephrol. 30(6) doi: 10.1681/ASN.2018080816
  • Song K, Gras C, Capin G, Gimber N, Lehmann M, Mohd S, Puchkov D, Rödiger M, Wilhelmi I, Daumke O, Schmoranzer J, Schürmann A, Krauss M
    A SEPT1-based scaffold is required for Golgi integrity and function
    J Cell Sci. 132(3) doi: 10.1242/jcs.225557
  • Houtman J, Freitag K, Gimber N, Schmoranzer J, Heppner FL, Jendrach M
    Beclin1-driven autophagy modulates the inflammatory response of microglia via NLRP3
    EMBO J. 38(4) doi: 10.15252/embj.201899430
  • Neumann A, Schindler M, Olofsson D, Wilhelmi I, Schürmann A, Heyd F
    Genome-wide identification of alternative splicing events that regulate protein transport across the secretory pathway
    J Cell Sci. 132(8) doi: 10.1242/jcs.230201
  • Özel MN, Kulkarni A, Hasan A, Brummer J, Moldenhauer M, Daumann IM, Wolfenberg H, Dercksen VJ, Kiral FR, Weiser M, Prohaska S, von Kleist M, Hiesinger PR
    Serial Synapse Formation through Filopodial Competition for Synaptic Seeding Factors
    Dev Cell. 50(4) doi: 10.1016/j.devcel.2019.06.014
  • Faelber K, Dietrich L, Noel JK, Wollweber F, Pfitzner AK, Mühleip A, Sánchez R, Kudryashev M, Chiaruttini N, Lilie H, Schlegel J, Rosenbaum E, Hessenberger M, Matthaeus C, Kunz S, von der Malsburg A, Noé F, Roux A, van der Laan M, Kühlbrandt W, Daumke O
    Structure and assembly of the mitochondrial membrane remodelling GTPase Mgm1
    Nature. 571(7765) doi: 10.1038/s41586-019-1372-3
  • Banko M, Mucha-Kruczynska I, Weise C, Heyd F, Ewers H.
    A homozygous genome-edited Sept2-EGFP fibroblast cell line
    Cytoskeleton (Hoboken) 76(1) doi: 10.1002/cm.21518
  • Sammons RP, Parthier D, Stumpf A, Schmitz D
    Electrophysiological and Molecular Characterization of the Parasubiculum
    J Neurosci. 39(45) doi: 10.1523/JNEUROSCI.0796-19.2019
  • Brockmann MM, Maglione M, Willmes CG, Stumpf A, Bouazza BA, Velasquez LM, Grauel MK, Beed P, Lehmann M, Gimber N, Schmoranzer J, Sigrist SJ, Rosenmund C, Schmitz D
    RIM-BP2 primes synaptic vesicles via recruitment of Munc13-1 at hippocampal mossy fiber synapses
    Elife. 8:e43243 doi: 10.7554/eLife.43243
  • Maglione M, Kochlamazashvili G, Eisenberg T, Rácz B, Michael E, Toppe D, Stumpf A, Wirth A, Zeug A, Müller FE, Moreno-Velasquez L, Sammons RP, Hofer SJ, Madeo F, Maritzen T, Maier N, Ponimaskin E, Schmitz D, Haucke V, Sigrist SJ
    Spermidine protects from age-related synaptic alterations at hippocampal mossy fiber-CA3 synapses
    Sci Rep 9(1) doi: 10.1038/s41598-019-56133-3
  • Rödel CJ, Otten C, Donat S, Lourenço M, Fischer D, Kuropka B, Paolini A, Freund C, Abdelilah-Seyfried S
    Blood Flow Suppresses Vascular Anomalies in a Zebrafish Model of Cerebral Cavernous Malformations
    Circ Res 125(10) doi: 10.1161/CIRCRESAHA.119.315076
  • Mathejczyk TF, Wernet MF
    Heading choices of flying Drosophila under changing angles of polarized light
    Sci Rep 9doi: 10.1038/s41598-019-53330-y
  • Brosig A, Fuchs J, Ipek F, Kroon C, Schrötter S, Vadhvani M, Polyzou A, Ledderose J, van Diepen M, Holzhütter HG, Trimbuch T, Gimber N, Schmoranzer J, Lieberam I, Rosenmund C, Spahn C, Scheerer P, Szczepek M, Leondaritis G, Eickholt BJ
    The Axonal Membrane Protein PRG2 Inhibits PTEN and Directs Growth to Branches
    Cell Rep 29(7) doi: 10.1016/j.celrep.2019.10.039
  • Gerth F, Jäpel M, Sticht J, Kuropka B, Schmitt XJ, Driller JH, Loll B, Wahl MC, Pagel K, Haucke V, Freund C
    Exon Inclusion Modulates Conformational Plasticity and Autoinhibition of the Intersectin 1 SH3A Domain
    Structure. 27(6) doi: 10.1016/j.str.2019.03.020

  • Teucher M, Zhang H, Bader V, Winklhofer KF, García-Sáez AJ, Rajca A, Bleicken S, Bordignon E
    A new perspective on membrane-embedded Bax oligomers using DEER and bioresistant orthogonal spin labels
     Scientific Reports 9 doi: 10.1038/s41598-019-49370-z

  • Böhme MA, McCarthy AW, Grasskamp AT, Beuschel CB, Goel P, Jusyte M, Laber D, Huang S, Rey U, Petzoldt AG, Lehmann M, Göttfert F, Haghighi P, Hell SW, Owald D, Dickman D, Sigrist SJ, Walter AM
    Rapid active zone remodeling consolidates presynaptic potentiation
    Nat. Commun. 19: 1085 doi: 10.1038/s41467-019-08977-6

  • Hoffmann M, Fröhner C, Noé F
    ReaDDy 2: Fast and flexible software framework for interacting-particle reaction dynamics 
    PLoS Comput Biol 15(2) doi: 10.1371/journal.pcbi.1006830

  • Driller JH, Lützkendorf J, Depner H, Siebert M, Kuropka B, Weise C, Piao C, Petzoldt AG, Lehmann M, Stelzl U, Zahedi R, Sickmann A, Freund C, Sigrist SJ, Wahl MC
    Phosphorylation of the Bruchpilot N-terminus unlocks axonal transport of active zone building blocks
    J Cell Sci 132(6) doi: 10.1242/jcs.225151

  • Krupp F, Said N, Huang YH, Loll B, Bürger J, Mielke T, Spahn CMT, Wahl MC
    Structural Basis for the Action of an All-Purpose Transcription Anti-termination Factor
    Molecular Cell 74 doi: 10.1016/j.molcel.2019.01.016

  • Song K, Gras C, Capin G, Gimber N, Lehmann M, Mohd S, Puchkov D, Rödiger M, Wilhelmi I, Daumke O, Schmoranzer J, Schürmann A, Krauss M
    A SEPT1-based scaffold is required for Golgi integrity and function
    J Cell Sci 132(3) doi:10.1242/jcs.225557

  • Kreis P, Gallrein C, Rojas-Puente E, Mack TGA, Kroon C, Dinkel V, Willmes C, Murk K, Tom-Dieck S, Schuman EM, Kirstein J, Eickholt BJ
    ATM phosphorylation of the actin-binding protein drebrin controls oxidation stress-resistance in mammalian neurons and C. elegans
    Nat Communn 10:486 doi: 10.1038/s41467-019-08420-w

  • Hoffmann S, Orlando M, Andrzejak E, Bruns C, Trimbuch T, Rosenmund C, Garner CC, Ackermann F
    Light-activated ROS production induces synaptic autophagy
    J Neurosci. 39(12) doi: 10.1523/JNEUROSCI.1317-18.2019

  • Rademacher N, Kuropka B, Kunde SA, Wahl MC, Freund C, Shoichet SA
    Intramolecular domain dynamics regulate 2 synaptic MAGUK protein interactions
    eLife 8:e41299 doi: 10.7554/eLife.41299

  • Choudhary V, Golani G, Joshi AS, Cottier S, Schneiter R, Prinz WA, Kozlov MM
    Architecture of Lipid Droplets in Endoplasmic Reticulum Is Determined by Phospholipid Intrinsic Curvature
    Curr Biol. 28(6) doi: 10.1016/j.cub.2018.02.020
  • Nikolay R, Hilal T, Qin B, Mielke T, Bürger J, Loerke J, Textoris-Taube K, Nierhaus KH, Spahn CMT
    Structural Visualization of the Formation and Activation of the 50S Ribosomal Subunit during In Vitro Reconstitution
    Mol Cell. 70(5) doi: 10.1016/j.molcel.2018.05.003
  • Qureshi BM, Behrmann E, Schöneberg J, Loerke J, Bürger J, Mielke T, Giesebrecht J, Noé F, Lamb TD, Hofmann KP, Spahn CMT, Heck M
    It takes two transducins to activate the cGMP-phosphodiesterase 6 in retinal rods
    Open Biol. 8(8) doi: 10.1098/rsob.180075
  • Liu F, Lössl P, Rabbitts BM, Balaban RS, Heck AJR
    The interactome of intact mitochondria by cross-linking mass spectrometry provides evidence for coexisting respiratory supercomplexes
    Mol Cell Proteomics. 17(2) doi: 10.1074/mcp.RA117.000470
  • Moroni M, Servin-Vences MR, Fleischer R, Sánchez-Carranza O, Lewin GR 
    Voltage gating of mechanosensitive PIEZO channels
    Nat Commun 9(1)doi: 10.1038/s41467-018-03502-7
  • Kath C, Goni-Oliver P, Müller R, Schultz C, Haucke V, Eickholt B, Schmoranzer J
    PTEN suppresses axon outgrowth by down-regulating the level of detyrosinated microtubules
    PLoS One. 13(4) doi: 10.1371/journal.pone.0193257

  • Vukoja A, Rey U, Petzoldt AG, Ott C, Vollweiter D, Quentin C, Puchkov D, Reynolds E, Lehmann M, Hohensee S, Rosa S, Lipowsky R, Sigrist SJ, Haucke V 
    Presynaptic biogenesis requires axonal transport of lysosome-related vesicles
    Neuron 99(6) doi: 10.1016/j.neuron.2018.08.004

  • Fulterer A, Andlauer TFM, Ender A, Maglione M, Eyring K, Woitkuhn J, Lehmann M, Matkovic-Rachid T, Geiger JRP, Walter AM, Nagel KI, Sigrist SJ
    Active zone scaffold protein ratios tune functional diversity across brain synapses
    Cell Rep 23(5) doi: 10.1016/j.celrep.2018.03.126
  • Migh E, Götz T, Földi I, Szikora S, Gombos R, Darula Z, Medzihradszky KF, Maléth J, Hegyi P, Sigrist S, Mihály J
    Microtubule organization in presynaptic boutons relies on the formin DAAM
    Development 145(6) doi:10.1242/dev.158519

  • Sadeghi M, Weikl TR, Noé F
    Particle-based membrane model for mesoscopic simulation of cellular dynamics
    J. Chem. Phys.148(4) doi: 10.1063/1.5009107

  • Mardt A, Pasquali L, Wu H, Noé F 
    VAMPNets for deep learning of molecular kinetics
    Nat. Commun. 9(1) doi: 10.1038/s41467-017-02388-1

  • Fröhner C and Noé F
    Reversible interacting-particle reaction dynamics
    J. Phys. Chem B.122(49) doi: 10.1021/acs.jpcb.8b06981

  • Watanabe S, Mamer LE, Raychaudhuri S, Luvsanjav D, Eisen J, Trimbuch T, Söhl-Kielczynski B, Fenske P, Milosevic I, Rosenmund C, Jorgensen EM
    Synaptojanin and endophilin mediate neck formation during ultrafast endocytosis
    Neuron 98 (6) doi: 10.1016/j.neuron.2018.06.005

  • Chang S, Trimbuch T, Rosenmund C
    Synaptotagmin‐1 drives synchronous Ca2+‐ triggered fusion by C2B domain‐mediated synaptic vesicle‐membrane attachment
    Nat Neurosci 21(1) doi: 10.1038/s41593-017-0037-5

  • Qureshi BM, Schmidt A, Behrmann E, Bürger J, Mielke T, Spahn CMT, Heck M, Scheerer P 
    Mechanistic insights into the role of prenyl-binding protein PrBP/delta in membrane dissociation of phosphodiesterase 6
    Nature Comm. 9(1) doi:10.1038/s41467-017-02569-y

  • Rödiger M, Werno MW, Wilhelmi I, Baumeier C, Hesse D, Wettschureck N, Offermanns S, Song K, Krauß M, Schürmann A
    Adiponectin release and insulin receptor targeting share trans-Golgi-dependent endosomal trafficking routes
    Mol Metab. 8 doi: 10.1016/j.molmet.2017.11.011

  • Stadion M, Schwerbel K, Graja A, Baumeier C, Rödiger M, Jonas W, Wolfrum C, Staiger H, Fritsche A, Häring HU, Klöting N, Blüher M, Fischer-Posovszky P, Schulz TJ, Joost HG, Vogel H, Schürmann A
    Increased Ifi202b/IFI16 expression stimulates adipogenesis in mice and humans
    Diabetologia. 61(5) doi: 10.1007/s00125-018-4571-9

  • Werno MW, Wilhelmi I, Kuropka B, Ebert F, Freund C, Schürmann A
    The GTPase ARFRP1 affects lipid droplet protein composition and triglyceride release from intracellular storage of intestinal Caco-2 cells
    Biochem Biophys Res Commun. 506(1) doi: 10.1016/j.bbrc.2018.10.092

  • Kreis P, Gallrein C, Rojas-Puente E, Mack TGA, Kroon C, Dinkel V, Willmes C, Murk K, Tom-Dieck S, Schuman EM, Kirstein J, Eickholt BJ
    ATM phosphorylation of the actin-binding protein drebrin controls oxidation stress-resistance in mammalian neurons and C. elegans
    Nat Commun. 10(1) doi: 10.1038/s41467-019-08420-w

  • Kath C, Goni-Oliver P, Müller R, Schultz C, Haucke V, Eickholt B, Schmoranzer J
    PTEN suppresses axon outgrowth by down-regulating the level of detyrosinated microtubules
    PLoS One, 13(4) doi: 10.1371/journal.pone.0193257

  • Gao M, Maraspini R, Beutel O, Zehtabian A, Eickholt B, Honigmann A, Ewers H
    Expansion Stimulated Emission Depletion Microscopy (ExSTED)
    ACS Nano 2018, 12(5) doi: 10.1021/acsnano.8b00776

  • Jin EJ, Kiral FR, Ozel MN, Burchardt LS, Osterland M, Epstein D, Wolfenberg H, Prohaska S, Hiesinger PR
    Live observation of two parallel membrane degradation pathways at axon terminals
    Curr. Biol., 28(7) doi: 10.1016/j.cub.2018.02.032

  • Kiral FR, Kohrs FE, Jin EJ, Hiesinger PR
    Rab GTPases and Membrane Trafficking in Neurodegeneration
    Curr Biol. 28(8) doi: 10.1016/j.cub.2018.02.010

  • Goldammer G, Neumann A, Strauch M, Müller-McNicoll M, Heyd F, Preußner M
    Characterization of cis-acting elements that control oscillating alternative splicing
    RNA Biol. 15(8) doi: 10.1080/15476286.2018.1502587

  • Otten C, Knox J, Boulday G, Eymery M, Haniszewski M, Neuenschwander M, Radetzki S, Vogt I, Hähn K, De Luca C, Cardoso C, Hamad S, Igual Gil C, Roy P, Albiges-Rizo C, Faurobert E, von Kries JP, Campillos M, Tournier-Lasserve E, Derry WB, Abdelilah-Seyfried S
    Systematic pharmacological screens uncover novel pathways involved in cerebral cavernous malformations
    EMBO Mol Med. 10(10) doi: 10.15252/emmm.201809155

  • Donat S, Lourenço M, Paolini A, Otten C, Renz M, Abdelilah-Seyfried S
    Heg1 and Ccm1/2 proteins control endocardial mechanosensitivity during zebrafish valvulogenesis
    eLIFE 7:e28939 doi: 10.7554/eLife.28939

  • Lisowska J, Rödel CJ, Manet S, Miroshnikova YA, Boyault C, Planus E, De Mets R, Lee HH, Destaing O, Mertani H, Boulday G, Tournier-Lasserve E, Balland M, Abdelilah-Seyfried S, Albiges-Rizo C, Faurobert E
    The CCM1-CCM2 complex controls complementary functions of ROCK1 and ROCK2 that are required for endothelial integrity
    J Cell Sci. 131(15) doi: 10.1242/jcs.216093

  • Paolini A & Abdelilah-Seyfried S
    The mechanobiology of zebrafish cardiac valve leaflet formation
    Curr Opin Cell Biol. 55 doi: 10.1016/j.ceb.2018.05.007

  • Demal TJ, Heise M, Reiz B, Dogra D, Brænne I, Reichenspurner H, Männer J, Aherrahrou Z, Schunkert H, Erdmann J, Abdelilah-Seyfried S
    A familial congenital heart disease with a possible multigenic origin involving a mutation in BMPR1A
    Scientific Reports 9(1) doi: 10.1038/s41598-019-39648-7

  • Heinloth T, Uhlhorn J, Wernet MF
    Insect Responses to Linearly Polarized Reflections: Orphan Behaviors without Neural Circuits
    Front Cell Neurosci. 20 doi: 10.3389/fncel.2018.00050

  • Özel MN, Kulkarni A, Hasan A, Brummer J, Moldenhauer M, Daumann IM, Wolfenberg H, Dercksen VJ, Kiral FR, Weiser M, Prohaska S, von Kleist M, Hiesinger PR
    Serial synapse formation through filopodial competition for synaptic seeding factors
    Dev Cell. 50(4) doi: 10.1016/j.devcel.2019.06.014

  • Ackermann F, Schink KO, Bruns C, Izsvák Z, Hamra FK, Rosenmund C, Garner CC
    Critical role for Piccolo in Synaptic Vesicle Retrieval
    Elife. 8:e46629 doi: 10.7554/eLife.46629

  • Ehmann N, Owald D, Kittel RJ
    Drosophila active zones: From molecules to behavior
    Neurosci Res 127 doi: 10.1016/j.neures.2017.11.015

  • Wu XS, Elias S, Liu H, Heureaux J, Wen PJ, Liu AP, Kozlov MM, Wu LG
    Membrane Tension Inhibits Rapid and Slow Endocytosis in Secretory Cells
    Biophys J. 113(11) doi: 10.1016/j.bpj.2017.09.035
  • Liu Q, Remmelzwaal S, Heck AJR, Akhmanova A, Liu F
    Facilitating identification of minimal protein binding domains by cross-linking mass spectrometry
    Sci Rep. 7(1) doi: 10.1038/s41598-017-13663-y
  • Jakob, B., G. Kochlamazashvili, M. Jäpel, A. Gauhar, H.H. Bock, T. Maritzen, and V. Haucke  
    Intersectin 1 is a component of the Reelin pathway to regulate neuronal migration and synaptic plasticity in the hippocampus. 
    PNAS 114 (21), pp. 5533-5538, https://doi.org/10.1073/pnas.1704447114
  • Kononenko, N.L.*, G.A. Classen*, M. Kuijpers, D. Puchkov, T. Maritzen, A. Tempes, A.R. Malik, A. Skalecka, S. Bera, J. Jaworski, and V. Haucke
    Retrograde transport of TrkB-containing autophagosomes via the adaptor AP-2 mediates neuronal complexity and prevents neurodegeneration.
    Nat Commun 8,  p. 14819 

  • Soykan, T., N. Kaempf, T. Sakaba, D. Vollweiter, F. Goerdeler, D. Puchkov, N.L. Kononenko, and V. Haucke   
    Synaptic Vesicle Endocytosis Occurs on Multiple Timescales and Is Mediated by Formin-Dependent Actin Assembly.
    Neuron 201, pp. 854-866

  • Reddy-Alla, S., Bohme, M.A., Reynolds, E., Beis, C., Grasskamp, A.T., Mampell, M.M., Maglione, M., Jusyte, M., Rey, U., Babikir, H., McCarthy, A.W., Quentin, C., Matkovic, T., Bergeron, D.D., Mushtaq, Z., Gottfert, F., Owald, D., Mielke, T., Hell, S.W., Sigrist, S.J., & Walter, A.M.
    Stable positioning of Unc13 restricts synaptic vesicle fusion to defined release sites to promote synchronous neurotransmission.
    Neuron 95, pp. 1350-1364
  • Paul, F., Wehmeyer, C., Abualrous, E.T., Wu, H., Crabtree, M. D., Schöneberg, J., Clarke, J., Freund, C., Weikl, T. R. and F. Noé.
    Protein-peptide association kinetics beyond the seconds timescale from atomistic simulations.
    Nat. Commun. 8: 1095
  • Plattner N., Doerr S., De Fabritiis G. and F. Noé.
    Complete protein–protein association kinetics in atomic detail revealed by molecular dynamics simulations and Markov modelling.
    Nat. Chem. 9, pp. 1005–1011

  • Schöneberg, J., Lehmann, M., Ullrich, A., Posor, Y., Lo, W. T., Lichtner, G., Schmoranzer, J., Haucke, V. and F. Noé.
    Lipid-mediated PX-BAR domain recruitment couples local membrane constriction to endocytic vesicle fission.
    Nat. Commun. 8: 15873

  • Liu F, Lössl P, Scheltema R, Viner R, Heck AJR
    Optimized fragmentation schemes and data analysis strategies for proteome-wide cross-link identification
    Nat Commun. 8 doi: 10.1038/ncomms15473

  • Rost, B.R.#+, F. Schneider‐Warme, D. Schmitz, and P. Hegemann.
    Optogenetic Tools for Subcellular Applications in Neuroscience.
    Neuron 96, pp. 572‐603

  • Camacho, M., J. Basu, T. Trimbuch, S. Chang, C. Pulido‐Lozano, S.S. Chang, I. Duluvova, M. Abo‐ Rady, J. Rizo, and C. Rosenmund.
    Heterodimerization of Munc13 C2A domain with RIM regulates synaptic vesicle docking and priming.
    Nat Commun 8: 15293

  • Willmes, C.G., T.G. Mack, J. Ledderose, D. Schmitz, C. Wozny, and B.J. Eickholt.
    Investigation of hippocampal synaptic transmission and plasticity in mice deficient in the actin‐binding protein Drebrin.
    Sci Rep 7: 42652

  • Gerth, F., M. Japel, A. Pechstein, G. Kochlamazashvili, M. Lehmann, D. Puchkov, F. Onofri, F. Benfenati, A.G. Nikonenko, K. Fredrich, O. Shupliakov, T. Maritzen, C. Freund, and V. Haucke.
    Intersectin associates with synapsin and regulates its nanoscale localization and function.
    Proc Natl Acad Sci U S A. 114:12057-12062

  • Lo, W.T., A. Vujicic Zagar, F. Gerth, M. Lehmann, D. Puchkov, O. Krylova, C. Freund, L. Scapozza, O. Vadas, and V. Haucke.
    A Coincidence Detection Mechanism Controls PX-BAR Domain-Mediated Endocytic Membrane Remodeling via an Allosteric Structural Switch.
    Dev Cell. 43, pp. 522-529 e524

  • Rocio Servin-Vences, M., M. Moroni, G.R. Lewin, K. Poole, M.R. Servin-Vences, M. Moroni, G.R. Lewin, K. Poole.
    Direct measurement of TRPV4 and PIEZO1 activity reveals multiple mechanotransduction pathways in chondrocytes.
    Elife. 6: e21074

  • Wetzel, C., S. Pifferi, C. Picci, C. Gök, D. Hoffmann, K.K. Bali, A. Lampe, L. Lapatsina, R. Fleischer, E.S.J. Smith, V. Bégay, M. Moroni, L. Estebanez, J. Kühnemund, J. Walcher, E. Specker, M. Neuenschwander, J.P. von Kries, V. Haucke, R. Kuner, J.F.A. Poulet, J. Schmoranzer, K. Poole#, and G.R. Lewin#.
    Small-molecule inhibition of STOML3 oligomerization reverses pathological mechanical hypersensitivity.
    Nat. Neurosci. 20, pp. 209–218

  • Rödiger, M., Werno, M.W., Wilhelmi, I., Baumeier, C., Hesse, D., Wettschureck, N., Offermanns, S., Song, K., Krauss, M. & Schürmann A.
    Adiponectin release and insulin receptor targeting share trans-Golgi-dependent endosomal trafficking routes.
    Mol. Metab. 8, pp. 167-179

  • Kaplan, C., Steinmann, M., Zapiorkowska, N. and Ewers, H.
    Functional redundancy of septin homologs in dendritic branching.
    Font. Cell Dev. Biol. 5, 11

  • Melo, A.A., Hegde B.G., Shah C., Larsson E., Isas J.M., Kunz S., Lundmark R., Langen R. & Daumke, O.#
    Structural insights into the activation mechanism of dynamin-like EHD ATPases.
    Proc Natl Acad Sci. 114,  5629-5634

  • Paul, F., Zauber, H., von Berg, L., Rocks, O., Daumke O., Selbach, M.#
    Quantitative GTPase Affinity Purification Identifies Rho Family Protein Interaction Partners.
    Mol Cell Prot. 16,  73-85

  • Jin E.J., Kiral, F.R. and Hiesinger, P.R.
    The Where, What and When of Membrane Protein Degradation in Neurons.
    Dev. Neurobiol. doi: 10.1002/dneu.22534

  • Kolodkin, A.L. and Hiesinger, P.R.
    Wiring visual systems: common and divergent mechanisms and principles.
    Curr. Opin. Neurobiol. 42:128-135

  • Okerlund, N.D., Schneider, K. Leal-Ortiz, S., Montenegro-Venegras, C., Kim, S.A., Garner, L.C., Gundelfinger, E.D. Reimer, R.J. and C.C. Garner.
    Bassoon controls presynaptic autophagy through Atg5.
    Neuron 93: 897-913, DOI: https://doi.org/10.1016/j.neuron.2018.01.010

  • Herdt, O., Neumann, A., Timmermann, B. & Heyd, F.
    The cancer-associated U2AF35 470A>G (Q157R) mutation creates an in-frame alternative 5’ splice site that impacts on splicing regulation in Q157R patients.
    RNA. 23, 1796-1806.

  • Preußner, M., Goldammer, G., Neumann, A., Haltenhof, T., Rautenstrauch, P., Müller-McNicoll, M. & Heyd, F.
    Body temperature cycles control rhythmic alternative splicing in mammals.
    Mol Cell. 67, 433-446, DOI: 10.1016/j.molcel.2017.06.006

  • Perisse E, Owald D, Barnstedt O, Talbot CB, Huetteroth W, Waddell S
    Aversive Learning and Appetitive Motivation Toggle Feed-Forward Inhibition in the Drosophila Mushroom Body
    Neuron. 90(5) doi: 10.1016/j.neuron.2016.04.034
  • Eccles RL, Czajkowski MT, Barth C, Müller PM, McShane E, Grunwald S, Beaudette P, Mecklenburg N, Volkmer R, Zühlke K, Dittmar G, Selbach M, Hammes A, Daumke O, Klussmann E, Urbé S, Rocks O
    Bimodal antagonism of PKA signalling by ARHGAP36
    Nat Commun. 7:12963 doi: 10.1038/ncomms12963

  • Paarmann P, Dörpholz G, Fiebig J, Amsalem AR, Ehrlich M, Henis YI, Müller T, Knaus P.
    Dynamin-dependent endocytosis of Bone Morphogenetic Protein2 (BMP2) and its receptors is dispensable for the initiation of Smad signaling. 
    Int J Biochem Cell Biol., pp. 1357-2725

  • Schrötter S, Leondaritis G and Eickholt BJ. 

    Capillary isoelectric focusing of Akt isoforms identifies highly dynamic phosphorylation in neuronal cells and brain tissue. 
    J Biol Chem. 2016 May 6;291(19):10239-51.

  • Grauel MK, Maglione M, Reddy-Alla S, Willmes CG, Brockmann MM, Trimbuch T, Rosenmund T, Pangalos M, Vardar G, Stumpf A, Walter AM, Rost BR, Eickholt BJ, Haucke V, Schmitz D, Sigrist SJ, Rosenmund C.
    RIM-binding protein 2 regulates release probability by fine-tuning calcium channel localization at murine hippocampal synapses. 
    Proc Natl Acad Sci U S A. 113:11615-11620, 10.1073/pnas.1605256113 

  • Gupta VK, Pech U, Bhukel A, Fulterer A, Ender A, Mauermann SF, Andlauer TFM, Antwi-Adjei E, Beuschel C, Thriene K, Maglione M, Quentin C, Bushow R, Schwärzel M, Mielke T, Madeo F, Dengjel J, Fiala A, Sigrist SJ.
    Spermidine Suppresses Age-Associated Memory Impairment by Preventing Adverse Increase of Presynaptic Active Zone Size and Release.
    PLoS Biol 14(9): e1002563. doi:10.1371/journal.pbio.1002563

  • Albrecht, D., Winterflood, C. M., Sadeghi, M., Tschager, T., Noé, F., and H. Ewers.
    Nanoscopic compartmentalization of membrane protein motion at the axon initial segment.
    J. Cell. Biol. 215: 37-46

  • Vardar, G., Chang, S., Arancillo, M., Wu, Y.J., Trimbuch, T. & Rosenmund, C.
    Distinct Functions of Syntaxin‐1 in Neuronal Maintenance, Synaptic Vesicle Docking, and Fusion in Mouse Neurons.
    J Neurosci 36, pp. 7911‐7924

  • Böhme, M.A., Beis, C., Reddy-Alla, S., Reynolds, E., Mampell, M.M., Grasskamp, A.T., Lützkendorf, J., Bergeron, D.D., Driller, J.H., Babikir, H., Göttfert, F., Robinson, I.M., O'Kane, C.J., Hell, S.W., Wahl, M.C., Stelzl, U., Loll B., Walter, A.M. & Sigrist, S.J.
    Active zone scaffolds differentially accumulate Unc13 isoforms to tune Ca2+ channel-vesicle coupling.
    Nat Neurosci 19, pp. 1311-1320 

  • Schulte, K., Pawlowski, N., Faelber, K., Fröhlich, C., Howard, J., Daumke, O.
    The immunity-related GTPase Irga6 dimerizes in a parallel head-to-head fashion.
    BMC Biol. 14: 14

  • Barnstedt O, Owald D, Felsenberg J, Brain R, Moszynski JP, Talbot CB, Perrat PN, Waddell S
    Memory-Relevant Mushroom Body Output Synapses Are Cholinergic
    Neuron. 89(6) doi: 10.1016/j.neuron.2016.02.015

  • Song, K., Russo, G. & Krauss, M.
    Septins as modulators of endo-lysosomal membrane traffic.
    Frontiers Cell Dev. Biol. 4, 124, https://doi.org/10.3389/fcell.2016.00124

  • Ketel, K., Krauss, M., Nicot, A.S., Puchkov, D., Wieffer, M., Müller, R., Subramanian, D., Schultz, C., Laporte, J, & Haucke, V. A Phosphoinositide conversion mechanism for exit from endosomes.
    Nature 529, pp. 408-412, DOI: 10.1038/nature16516

  • Sampathkumar, C., Y.J. Wu, M. Vadhvani, T. Trimbuch, B. Eickholt, and C. Rosenmund.
    Loss of MeCP2 disrupts cell autonomous and autocrine BDNF signaling in mouse glutamatergic neurons.
    Elife. 5 pii: e19374. doi: 10.7554/eLife.19374

  • Garaulet, D.L., Sun, K., Li, W., Wen, J., Panzarino, A.M., O'Neil, J.L., Hiesinger, P.R., Young, M.W., and Lai, E.C.
    miR-124 Regulates Diverse Aspects of Rhythmic Behavior in Drosophila.
    J. Neurosci. 36(12):3414 –3421

  • Terry-Lorenzo RT, Torres VI, Wagh D, Galaz J, Swanson SK, Florens L, Washburn MP, Waites CL, Gundelfinger ED, Reimer RJ, Garner CC.
    Trio, a Rho Family GEF, Interacts with the Presynaptic Active Zone Proteins Piccolo and Bassoon. 
    PLoS One 11: e0167535
  • Rademacher, N., Schmerl, B., Lardong, J. A., Wahl, M. C., and Shoichet, S. A.
    MPP2 is a postsynaptic MAGUK scaffold protein that links SynCAM1 cell adhesion molecules to core components of the postsynaptic density.
    Sci Rep 6, 35283
  • Wilhelmi, I., Kanski, R., Neumann, A., Herdt, O., Hoff, F., Jacob, R., Preussner, M. & Heyd, F.
    Sec16 alternative splicing dynamically controls COPII transport efficiency.
    Nat Commun. 7, 12347
  • Haack,T. and S. Abdelilah-Seyfried.
    The force within: endocardial development, mechanotransduction and signalling during cardiac morphogenesis.
    Development 143, 373-86, DOI: 10.1242/dev.131425
  • Lehmann, M., G. Lichtner, H. Klenz, and J. Schmoranzer.
    Novel Organic Dyes for Multicolor Localization-Based Super-Resolution Microscopy.
    J. of Biophotonics 9 (1–2): 161–70, DOI: 10.1002/jbio.201500119
  • Kuropka, B., Schraven, B., Kliche, S., Krause, E. & Freund, C.
    Tyrosine-phosphorylation of the scaffold protein ADAP and its role in T cell signaling.
    Expert Rev Proteomics 13, 545-554, DOI: 10.1080/14789450.2016.1187565

  • Schweitzer Y, Shemesh T, Kozlov MM
    A Model for Shaping Membrane Sheets by Protein Scaffolds
    Biophys J. 109(3) doi: 10.1016/j.bpj.2015.06.001
  • Owald D, Felsenberg J, Talbot CB, Das G, Perisse E, Huetteroth W, Waddell S
    Activity of defined mushroom body output neurons underlies learned olfactory behavior in Drosophila.
    Neuron. 86(2) doi: 10.1016/j.neuron.2015.03.025
  • Liu F, Rijkers DT, Post H, Heck AJ
    Proteome-wide profiling of protein assemblies by cross-linking mass spectrometry
    Nat Methods.12(12) doi: 10.1038/nmeth.3603
  • Christ A, Christa A, Klippert J, Eule JC, Bachmann S, Wallace VA, Hammes A, Willnow TE
    LRP2 Acts as SHH Clearance Receptor to Protect the Retinal Margin from Mitogenic Stimuli
    Dev Cell. 35(1) doi: 10.1016/j.devcel.2015.09.001
  • Schrenk-Siemens K, Wende H, Prato V, Song K, Rostock C, Loewer A, Utikal J, Lewin GR, Lechner SG, Siemens J
    PIEZO2 is required for mechanotransduction in human stem cell-derived touch receptors
    Nat Neurosci. 18(1) doi: 10.1038/nn.3894
  • Renz M, Otten C, Faurobert E, Rudolph F, Zhu Y, Boulday G, Duchene J, Mickoleit M, Dietrich AC, Ramspacher C, Steed E, Manet-Dupé S, Benz A, Hassel D, Vermot J, Huisken J, Tournier-Lasserve E, Felbor U, Sure U, Albiges-Rizo C, Abdelilah-Seyfried S
    Regulation of β1 integrin-Klf2-mediated angiogenesis by CCM proteins
    Dev Cell. 32(2) doi: 10.1016/j.devcel.2014.12.016
  • Kononenko, N. L., and Haucke, V. 
    Molecular mechanisms of presynaptic membrane retrieval and synaptic vesicle reformation
    Neuron 85, pp. 484-496
  • Jung, S, Maritzen T, Wichmann C, Jing Z, A. Neef A, Revelo N H, Al-Moyed H, Meese S, Wojcik S M, Panou I, Bulut H, Schu P, Ficner R, Reisinger E, Rizzoli S O, Neef J, Strenzke N, Haucke V, and Moser T
    Disruption of adaptor protein 2µ (AP-2µ) in cochlear hair cells impairs vesicle reloading of synaptic release sites and hearing.
    EMBO J. 34(21), pp. 2686–2702
  • Muhammad, K., Reddy-Alla, S., Driller, J.H., Schreiner, D., Rey, U., Bohme, M.A., Hollmann, C., Ramesh, N., Depner, H., Lützkendorf, J., Matkovic, T., Gotz, T., Bergeron, D.D., Schmoranzer, J., Goettfert, F., Holt, M., Wahl, M.C., Hell, S.W., Scheiffele, P., Walter, A.M., Loll, B., & Sigrist, S.J.
    Presynaptic spinophilin tunes neurexin signalling to control active zone architecture and function.
    Nat Commun 6, p. 8362
  • Reubold, T. F., Faelber, K., Plattner, N., Posor, Y., Ketel K., Curth, U., Schlegel, J., Anand, R., Manstein, D.J., Noé, F., Haucke, V., Daumke, O. and S. Eschenburg.
    Crystal structure of the dynamin tetramer.
    Nature 525, pp. 404-408, DOI: 10.1038/nature14880
  • Koo SJ, Kochlamazashvili G, Rost B, Puchkov D, Gimber N, Lehmann M, Tadeus G, Schmoranzer J, Rosenmund C, Haucke V, Maritzen T
    Vesicular Synaptobrevin/VAMP2 Levels Guarded by AP180 Control Efficient Neurotransmission
    Neuron. 88(2) doi: 10.1016/j.neuron.2015.08.034
  • Schweitzer Y & Kozlov MM
    Membrane-mediated interaction between strongly anisotropic protein scaffolds
    PLoS Comput Biol. 11(2) doi: 10.1371/journal.pcbi.1004054

  • Biedermann, J., Ullrich, A., Schöneberg, J. and F. Noé.
    ReaDDyMM: Fast interacting particle reaction-diffusion simulations using graphical processing units.
    Biophys. J. 108, pp. 457-461

  • Rost, B.R., Schneider, F., Grauel, M.K., Wozny, C., Bentz, C., Blessing, A., Rosenmund, T., Jentsch, T.J., Schmitz, D., Hegemann, P. & Rosenmund, C.
    Optogenetic acidification of synaptic vesicles and lysosomes.
    Nat Neurosci 18, 1845‐1852

  • Morrison E, Kuropka B, Kliche S, Brügger B, Krause E, Freund C
    Quantitative analysis of the human T cell palmitome
    Sci Rep. 5 doi: 10.1038/srep11598

  • Siebert, M., Böhme, M.A., Driller, J.H., Babikir, H., Mampell, M.M., Rey, U., Ramesh, N., Matkovic, T., Holton, N., Reddy-Alla, S., Göttfert, F., Kamin, D., Quentin, C., Klinedinst, S., Andlauer, T.F., Hell, S.W., Collins, C.A., Wahl, M.C., Loll, B., Sigrist, S.J.
    A high affinity RIM-binding protein/Aplip1 interaction prevents the formation of ectopic axonal active zones.
    eLife 4, e06935

  • Lardong, J.A., Driller, J.H., Depner, H., Weise, C., Petzoldt, A., Wahl, M.C., Sigrist, S.J., Loll B.
    Structures of Drosophila melanogaster Rab2 and Rab3 bound to GMPPNP.
    Acta Crystallogr F 71, pp. 34-40

  • Frank, J.A., M. Moroni, R. Moshourab, M. Sumser, G.R. Lewin, and D. Trauner.
    Photoswitchable fatty acids enable optical control of TRPV1.
    Nat. Commun. 6: 7118

  • Diesenberg, K., Beerbaum, M., Fink, U., Schmieder, P. & Krauss, M.
    Septin 9 negatively regulates ubiquitin-dependent downregulation of epidermal growth factor receptor.
    J. Cell Sci. 128, 397-407

  • Mikhaylova M., Cloin, B.M.C., Finan, K., van den Berg, R., Teeuw, J., Kijanka, M.M., Sokolowski, M., Katrukha, E.A., Maidorn, M. Opazo, F., Moutel, S., Vantard, M. Perez, F.,van Bergen en Henegouwen, P.M.P., Hoogenraad, C.C., Ewers, H., and Kapitein, L.C
    Resolving bundled microtubules using anti-tubulin nanobodies.
    Nature Commun.6: 7933, doi: 10.1038/ncomms8933

  • Kaplan, C., Jing, B., Winterflood, C.W., Bridges, A.A., Occhipinti, P., Schmied, J., Grinhagens, S., Gronemeyer, T., Tinnefeld, P., Gladfelter, A.S., Ries, J. and Ewers, H.
    Absolute arrangement of subunits in cytoskeletal septin filaments in cells measured by fluorescence microscopy.
    Nano Letters 15(6), pp. 3859-64, DOI: 10.1021/acs.nanolett.5b00693

  • Dick, A., Graf L., Olal D., von der Malsburg, A., Gao S., Kochs, G.# & Daumke, O.#
    Role of nucleotide binding and GTPase domain dimerization in dynamin-like myxovirus resistance protein A for GTPase activation and antiviral activity.
    J. Biol. Chem. 290, pp. 12779-12792

  • Özel, M.N., Langen, M., Hassan, B.A. and Hiesinger, P.R. 
    Filopodial Dynamics and Growth Cone Stabilization in Drosophila Visual Circuit Development. 
    eLife, e10721

  • Langen, M., Agi, E., Altschuler, D., Wu, L., Altschuler, S., and Hiesinger, P.R.
    The Developmental Rules of Neural Superposition.
    Cell, 162(1):120-33

  • Hassan, B.A. and Hiesinger, P.R.
    Beyond Molecular Codes: Simple Rules to Wire Complex Brains.
    Cell, 163(2):285-291

  • Wagh, D., Terry-Lorenzo, R., Waites, C.L. Leal-Ortiz, S.A., Maas, C., Reimer, R.J, and C.C. Garner.
    Piccolo directs activity dependent F-Actin assembly from presynaptic active zones via Daam1.
    PLos One 10: e0120093

  • Schuster, S., Rivalan, M., Strauss, U., Stoenica, L., Trimbuch, T., Rademacher, N., Parthasarathy, S., Lajko, D., Rosenmund, C., Shoichet, S. A., Winter, Y., Tarabykin, V., and Rosario, M.
    NOMA-GAP/ARHGAP33 regulates synapse development and autistic-like behavior in the mouse.
    Mol Psychiatry 20, 1120-1131, DOI: 10.1038/mp.2015.42

  • Gimber, N., G. Tadeus, T. Maritzen, J. Schmoranzer, and V. Haucke. 
    Diffusional Spread and Confinement of Newly Exocytosed Synaptic Vesicle Proteins.
    Nature Comm. 6: 8392

  • Lehmann, M., B. Gottschalk, D. Puchkov, P. Schmieder, S. Schwagerus, C.P.R. Hackenberger, V. Haucke, and J. Schmoranzer.
    Multicolor Caged dSTORM Resolves the Ultrastructure of Synaptic Vesicles in the Brain.
    Angew. Ch. Int. Ed. 54 (45): 13230–35

  • Winterflood, C.M., Platonova, E., Albrecht, D. and Ewers H.
    Dual color 3D superresolution microscopy by combined spectral-demixing and biplane imaging.
    Biophysical Journal 109 (1) pp:3-6

  • Baumeier, C., Kaiser, D., Heeren, J., Scheja, L., John, C., Weise, C.**, Eravci, M., Lagerpusch, M., Schulze, G., Joost, H.G., Schwenk, R.W. & Schurmann, A.
    Caloric restriction and intermittent fasting alter hepatic lipid droplet proteome and diacylglycerol species and prevent diabetes in NZO mice.
    Biochimica et biophysica acta 1851, 566-576, DOI: 10.1016/j.bbalip.2015.01.013

  • Morrison, E., Kuropka, B., Kliche, S., Brugger, B., Krause, E. & Freund, C.
    Quantitative analysis of the human T cell palmitome.
    Scientific reports 5, 11598

  • Kuropka, B., Royla, N., Freund, C. & Krause, E.
    Sortase A mediated site-specific immobilization for identification of protein interactions in affinity purification-mass spectrometry experiments.
    Proteomics 15, 1230-1234, DOI: 10.1002/pmic.201400395

  • Owald D & Waddell S
    Olfactory learning skews mushroom body output pathways to steer behavioral choice in Drosophila
    Curr Opin Neurobiol. 35 doi: 10.1016/j.conb.2015.10.002

  • Kur E, Mecklenburg N, Cabrera RM, Willnow TE, Hammes A
    LRP2 mediates folate uptake in the developing neural tube
    J Cell Sci. 127(Pt 10) doi: 10.1242/jcs.140145
  • Dietrich AC, Lombardo VA, Veerkamp J, Priller F, Abdelilah-Seyfried S
    Blood flow and Bmp signaling control endocardial chamber morphogenesis
    Dev Cell. 30(4) doi: 10.1016/j.devcel.2014.06.020

  • Kononenko, N. L., Puchkov, D., Classen, G. A., Walter, A., Pechstein, A., Sawade, L., Kaempf, N., Trimbuch, T., Lorenz, D., Rosenmund, C., Maritzen, T., and Haucke, V.
    Clathrin/ AP-2 mediate synaptic vesicle reformation from endosome-like vacuoles but are not essen­tial for membrane retrieval at central synapses
    Neuron 82(5), pp. 981-88

  • Podufall, J,. Tian, R., Knoche, E., Puchkov, D., Walter, A. M., Rosa, S., Quentin, C., Vukoja, A., Jung, N., Lampe, A., Wichmann, C., Böhme, M., Depner, H., Zhang, Y. Q., Schmoranzer, J., Sigrist, S. J., and Haucke, V.
    A presynaptic role for the cytomatrix protein GIT in synaptic vesicle recycling
    Cell Reports 7(5), pp. 1417-25 

  • Wilhelm, B. G., Mandad, S., Truckenbrodt, S., Kröhnert, K., Schäfer, C., Rammner, B., Koo, S. J., Claßen, G. A., Krauss, M., Haucke, V., Urlaub, H., Rizzoli, S. O.
     Composition of Synaptic Boutons Reveals the Amounts of Vesicle Trafficking Proteins
    Science 344, pp. 1023-28

  •  Watanabe, S., Trimbuch, T., Camacho-Perez, M., Rost, B. R., Brokowski, B., Sohl-Kielczynski, B., Felies,A., Davis, M. W., Rosenmund, C.,  and Jorgensen, E. M. Clathrin regenerates synaptic vesicles from endosomes 
    Nature 515 (7526), pp. 228-233

  •  Depner, H., J. Lützkendorf, H.A. Babikir, S.J. Sigrist  and M.G. Holt
    Differential centrifugationbased biochemical fractionation of the Drosophila adult CNS
    Nat Protoc 9, pp. 2796–2808

  •  Pechstein, A., Gerth, F., Milosevic, I., Jäpel, M., Eichhorn-Grünig, M., Vorontsova, O., Bacetic, J., Maritzen, T., Shupliakov, O., Freund, C., and Haucke, V.  
    Vesicle uncoating regulated by SH3-SH3 domainmediated complex formation between endophilin and intersectin at synapses
    EMBO Rep 15

  •  Daumke, O., Roux, A., and Haucke, V.  
    BAR domain scaffolds in dynamin-mediated membrane fission
    Cell 156. pp. 882-92

  •  Haucke, V.
    On the endocytosis rollercoaster
    Nature, doi:10.1038/nature14081

  •  Krauss, M., and Haucke, V.
    A novel twist in membrane dePHormation
    Dev Cell 31, pp. 3-4

  •  Poole, K., R. Herget, L. Lapatsina, H.-D. Ngo, and  G.R. Lewin
    Tuning Piezo ion channels to detect molecular-scale movements relevant for fine touch
    Nat. Commun. 5, p. 3520

  •  Ranade, S.S., S.-H. Woo, A.E. Dubin, R.A. Moshourab, C. Wetzel, M. Petrus, J. Mathur, V. Begay, B. Coste, J. Mainquist, A.J. Wilson, A. Francisco, K. Reddy, Z. Qiu, J.N. Wood, G.R. Lewin , and A. Patapoutian
    Piezo2 is the major transducer of mechanical forces for touch sensation in mice 
    Nature 516, pp. 121–25

  •  Vaegter, C.B., P. Jansen, A.W. Fjorback, S. Glerup, S. Skeldal, M. Kjolby, M. Richner, B. Erdmann, J.R. Nyengaard, L. Tessarollo, G.R. Lewin, T.E. Willnow, M.V. Chao, and A. Nykjaer
    Sortilin associates with Trk receptors to enhance anterograde transport and neurotrophin signaling
    Nat. Neurosci.14, pp. 54–61

  • Terasaki M, Shemesh T, Kasthuri N, Klemm RW, Schalek R, Hayworth KJ, Hand AR, Yankova M, Huber G, Lichtman JW, Rapoport TA, Kozlov MM
    Stacked endoplasmic reticulum sheets are connected by helicoidal membrane motifs
    Cell. 154(2) doi: 10.1016/j.cell.2013.06.031
  • Veerkamp J, Rudolph F, Cseresnyes Z, Priller F, Otten C, Renz M, Schaefer L, Abdelilah-Seyfried S
    Unilateral dampening of Bmp activity by nodal generates cardiac left-right asymmetry
    Dev Cell. 24(6) doi: 10.1016/j.devcel.2013.01.026

  • Sakaba, T., Kononenko, N. L., Bacetic, J., Pechstein, A., Schmoranzer, J., Yao, L., Barth, H., Shupliakov, O., Kobler, O., Aktories, K., and Haucke, V.
    Fast neurotransmitter release regulated by the endocytic scaffold intersectin
    Proc Natl Acad Sci U S A 110, pp. 8266-71

  • Hua, Y., Woehler, A., Kahms., M., and Haucke, V., Neher, E., Klingauf, J.
    Blocking endocytosis enhances short-term synaptic depression under conditions of normal availability of vesicles
    Neuron 80, pp. 343-49

  • Posor, Y., M. Eichhorn-Gruenig, D. Puchkov, J. Schöneberg, A. Ullrich, A. Lampe, R. Müller, S. Zarbakhsh,F. Gulluni, E. Hirsch, M. Krauss, M. C. Schultz, J. Schmoranzer, Noé, F.  and V. Haucke.
    Spatiotemporal control of endocytosis by phosphatidylinositol-3,4-bisphosphate 
    Nature 499, pp. 233-37 

  • Kintscher, M., Wozny, C., Johenning, F. W., Schmitz, D.,  and Breustedt, J..
    Role of RIM1alpha in shortand long-term synaptic plasticity at cerebellar parallel fibres 
    Nat Commun 4, pp. 2392

  • Matkovic, T., M. Siebert, E. Knoche, H. Depner, S. Mertel, D. Owald, M. Schmidt, U. Thomas, A. Sickmann,D. Kamin, S.W. Hell, J. Bürger, C. Hollmann, T. Mielke, 
    C. Wichmann and S. J. Sigrist  
    The Bruchpilot cytomatrix determines the size of the readily releasable pool of synaptic vesicles 
    J Cell Biol 202, pp. 667-83

  • Maglione, M. and S.J. Sigrist
    Seeing the forest tree by tree: super-resolution light microscopy meets the neurosciences 
    Nat Neurosci 16, pp.790-97

  • Fröhlich, C., Grabiger, S., Schwefel, D., Faelber, K., Rosenbaum, E., Mears, J., Rocks, O. & Daumke, O.
    Structural insights into oligomerization and mitochondrial remodelling of dynamin 1-like protein
    EMBO J 32, pp. 1280-92 

  • Elia N, Fabrikant G, Kozlov MM, Lippincott-Schwartz J
    Computational model of cytokinetic abscission driven by ESCRT-III polymerization and remodeling
    Biophys J. 102(10) doi: 10.1016/j.bpj.2012.04.007
  • Christ A, Christa A, Kur E, Lioubinski O, Bachmann S, Willnow TE, Hammes A
    LRP2 is an auxiliary SHH receptor required to condition the forebrain ventral midline for inductive signals
    Dev Cell. 22(2) doi: 10.1016/j.devcel.2011.11.023

  • Owald, D., Khorramshahi, O., Gupta, V. K., Banovic, D., Depner, H., Fouquet, W., Wichmann, C., Mertel, S. Eimer, S., Reynolds, E., Holt, M., Aberle, H., and Sigrist, S. J
    Cooperation of Syd-1 with Neurexin synchronizes pre- with postsynaptic assembly
    Nat Neurosci 15, pp.1219-26

  • Brand, J., E.S.J. Smith, D. Schwefel, L. Lapatsina, K. Poole,  D. Omerbašić , A. Kozlenkov, J. Behlke, G.R. Lewin, O. Daumke
    A stomatin dimer modulates the activity of acid-sensing ion channels
    EMBO J. 31, pp. 3635–46

  • Boucrot E, Pick A, Çamdere G, Liska N, Evergren E, McMahon HT, Kozlov MM
    Membrane fission is promoted by insertion of amphipathic helices and is restricted by crescent BAR domains
    Cell. 149(1) doi: 10.1016/j.cell.2012.01.047

  • Jaschke, A., Chung, B., Hesse, D., Kluge, R., Zahn, C., Moser, M., Petzke, K. J., Brigelius-Flohé, R., Puchkov, D., Koepsell, H., Heeren, J., Joost, H. G., and Schürmann, A
    The GTPase ARFRP1 controls the lipidation of chylomicrons in the Golgi of the intestinal epithelium 
    Hum. Mol. Genet . 21 , 3128-3142

  • Hesse, D., Jaschke, A., Kanzleiter, T., Witte, N., Augustin, R., Hommel, A., Püschel, G. P., Petzke, K. J., Joost, H. G., Schupp, M., and Schürmann, A 
    GTPase ARFRP1 is essential for normal hepatic glycogen storage and insulin-like growth factor 1 secretion
    Mol. Cell. Biol . 32 , 4363-4374

  • Lampe, A., Haucke, V., Sigrist, S.J., Heilemann, M. & Schmoranzer, J
    Multi-colour direct STORM with red emitting carbocyanines 
    Biol. Cell 104,  229–237

  • Burke CJ, Huetteroth W, Owald D, Perisse E, Krashes MJ, Das G, Gohl D, Silies M, Certel S, Waddell S
    Layered reward signalling through octopamine and dopamine in Drosophila
    Nature. 492(7429) doi: 10.1038/nature11614

  • Koo, S. J., Markovic, S., Puchkov, D., Mahrenholz, C. C., Beceren-Braun, F., Maritzen, T., Dernedde, J., Volkmer, R., Oschkinat, H., and Haucke, V.
    SNARE motif-mediated sorting of synaptobrevin by the endocytic adaptors clathrin assembly lymphoid myeloid leukemia (CALM) and AP180 at synapses
    PNAS 108(33), pp. 13540-45

  • Krabben, L., Fassio, A., Bhatia, V. K., Pechstein, A., Onofri, F., Fadda, M., Messa, M., Rao, Y., Shupliakov, O., Stamou, D., Benfenati, F., and Haucke, V.
    Synapsin I senses membrane curvature by an amphipathic lipid packing sensor motif
     J. Neurosci. 31, pp. 18149-54

  • Faelber, K., Posor, Y., Gao, S., Held, M., Roske, Y., Schulze, D., Haucke, V., Noé, F., Daumke, O.
    Crystal structure of nucleotide-free dynamin
    Nature 477, pp. 556-60

  • Liu, K. S. Y., Siebert, M., Mertel, S., Knoche, E., Wegener, S., Wichmann, C., Matkovic, T., Muhammad, K., Depner, H., Mettke, Ch., Bückers, J., Hell, S. W., Müller, M., Davis, G. W., Schmitz, D., and Sigrist, S. J.
    RIM-Binding Protein, a Central Part of the Active Zone, Is Essential for Neurotransmitter Release
    Science 334, pp. 1565-69